Taxonomy	Species	Clostridium difficile
	Category	Bacteria
	Genus	Clostridium
	Family	Clostridiaceae
	Order/Class	Clostridiales
	Phylum	Firmicutes
Human and animal disease	Human disease	Clostridium difficile associated disease
	Predominant syndrome	Gastro-intestinal
	Occ. risk group	n/a
	Incubation time	days to weeks
	Disease in farm animals	Yes
	Disease in pets and horses	Unknown
	Disease in wildlife	Unknown
	Specfic animal species	Pigs, ruminants
Reservoirs	Humans	Yes
	Farm animals	Yes
	Pets and horses	Yes
	Wildlife	Yes
	Specific animal species	Environ. commensal in some people

Transmission	Human to human	Yes
	Skin	No
	Tissue/blood: Arthropods	No
	Tissue/blood: Invasive actions	No
	Secreta/excreta: Air	No
	Secreta/excreta: Water/food/environment	Yes
	Secreta/excreta: Close animal contact	No
	Transmission info	Antibiotica triggered, fecal route
Geographic distribution	Netherlands	Yes
	Europe	Yes
	Africa	Unknown
	North America	Yes
	South America	Unknown
	Australia	Yes
	Asia	Yes
	Distribution info	Worldwid
Info	Specifics
	Human ref. website URL
	Animal ref. website URL

		Value		Normalised value	Weight	Score
1	Probability of introduction into the Netherlands	100	%	1	0.418	0.42
2	Transmission in animal reservoirs	0.005	%	0.39	0.292	0.11
3	Economic damage, animal reservoirs	5	M€	0.3	0.337	0.1
4	Animal-human transmission	0.005	%	0	0.626	0
5	Human-human transmission	0	%	0	0.339	0
6	Morbidity	0.06		0.28	0.181	0.05
7	Mortality	0	%	0	0.643	0
	Total					0.68
	Normalised score					0.27

EZIPs. Bilthoven: RIVM, <http://ezips.rivm.nl> versie 1.0, 17 May 2010